Dr. med. dent., PhD, Paul Zaslansky


Charité – Universitätsmedizin Berlin
Zahnerhaltung und Präventivzahnmedizin
Aßmannshauser Straße 4-6
14497 Berlin

Campus- bzw. interne Geländeadresse:
Haus 2, 3. OG, Raum 3.2.25

Sie befinden sich hier:


Competitive funding grants: 2015 – 2018(180.000 Euros):GIF (German-Israeli Foundation for Scientific Research and Development) Project: "Filling a gap in materials space: insights from the natural biocomposite acellular bone material of fish", Grant no. I-1278-401.10/20142009 – 2015 (550.000 Euros):DFG (German Research Foundation) Priority program in "Biomimetic Materials Research: Functionality by Hierarchical Structuring of Materials" (SPP 1420): spp1420.mpikg.mpg.de Project: "Hierarchy of microstructural features as the origin of fracture resistance in dentine and ceramic composites" Minerva Foundation: 2007 school on biological sciences and bio-inspired materials NSF: Grant for MRS symposium SS12 (MRS spring meeting 2012) since 2007: Numerous (> 25) granted research projects in international (large shared) radiation facilities, each spanning 3 to 7 days, including neutron reactor BER II and synchrotron facilities at BESSY (HZB Berlin), DESY (HZG Hamburg), ESRF (Grenoble, France). Beamtimes were granted for tomography (absorption and phase contrastenhanced), diffraction mapping, diffraction tomography, XRF + EXAFS for in situ testing of dentine, bone and other biological materials as well as zirconia ceramics and metal alloys. A typical experimental day is valued at € 5000~10000, depending on facility.Active or ongoing collaborations and scientific ties:  Prof. Claudia Fleck, Materials Science, TU Berlin, and Dr. W.D. Müller, Dental Biomaterials, Charité Universitätsmedizin, Berlin, Germany Prof. Bettina Willie, Department of Pediatric Surgery, Shriners Hospital, McGill University, Montreal, Canada Prof. Ron Shahar, Laboratory of Bone Biomechanics, Koret School of Veterinary Medicine, The Robert H. Smith Faculty of Agriculture, Food and Environment, Hebrew University of Jerusalem, Israel Researchers at synchrotron facilities: Dr. Bernd Mueller, Dr. Heinrich Riesemeier, Dr. Ivo Zizak, BAM, Berlin and BESSY, Helmholtz-Zentrum Berlin research facilities; Dr. Alexander Rack, Dr. Peter Cloetens, ESRF, Grenoble, France Researchers in the Max-Planck-Institute of Colloids and Interfaces, Potsdam: Prof. Prof. Peter Fratzl, Dr. Igor Zlotnikov, Dr. Mason Dean, Dr. Yael Politi Researchers in Dental Schools: Prof. S. Paris, Prof. F. Beuer, Dr. Uwe Blunck, Department of Restorative Dentistry, CharitéUniversitätsmedizin Berlin; Dr. Hagay Shemesh, Head, Section of Endodontics, ACTA, Amsterdam, The Netherlands. Joint research interests worldwide: Prof. Emil Zlotoyabko, Dr. Boaz Pokroy, Technion, Israel; Prof. John Currey, York, UK; Prof. Stefan Habelitz, UCSF, USA; Prof. Amir Berman, Beer-sheva, Israel; Dr. Ingrid Weiss, Saarland University and INM, Saarbrücken, Germany; Prof. Fritz Keilmann, Max-Planck-Institute for Quantum Optics, Garching, Germany; Dr. Erika Griesshaber, LMU, Munich, Germany; Prof. F. Pfeiffer, TU Munich, Germany; Prof. Admir Masic, MIT, USA


Weitere Informationen


J.B. Forien, I. Zizak, C. Fleck, A. Petersen, P. Fratzl, E. Zolotoyabko, P. Zaslansky,"Water-Mediated Collagen and Mineral Nanoparticle Interactions Guide Functional Deformation of Human Tooth Dentin", Chem. Mater. (2016), 28(10), 3416–27 A.C. Kaya, P. Zaslansky, A. Nikolaus, C. Fleck, "Tensile failure observations in sintered steel foam struts revealed by sub-micron contrast-enhanced microtomography", Mater. Design (2016) 105, 190-200 A. Moinzadeh, L. Farack, F. Wilde, H. Shemesh, P. Zaslansky, "Synchrotron-based phase contrast-enhanced microCT reveals delaminations and material tearing in waterexpandable root fillings ex vivo", J. Endod. (2016) ;42(5):776-81 F. Schaff, M. Bech, P. Zaslansky, C. Jud, M. Liebi, M. Guizar-Sicairos, F. Pfeiffer." Sixdimensionalreal and reciprocal space small-angle x-ray scattering tomography for nanostructure characterization" Nature (2015), 527, 353-6 F. Natalio, T.P. Corrales, S. Wanka, P. Zaslansky, M. Kappl, H.P. Lima, H.J. Butt, W. Tremel, "Siliceous spicules enhance fracture-resistance and stiffness of pre-colonial Amazonian ceramics", Sci Rep. (2015), 5:13303 A.T. Moinzadeh, W. Zerbst, C. Boutsioukis, H. Shemesh, P. Zaslansky, "Porosity distribution in root canals filled with gutta percha and calcium silicate cement", Dent Mater. (2015), 31(9):1100-8 J.B. Forien, C. Fleck, C. Krywka, E. Zolotoyabko, P. Zaslansky, "In situ compressibility of carbonated hydroxyapatite in tooth dentine measured under hydrostatic pressure by high energy X-ray diffraction" J Mech Behav Biomed Mater. (2015), 50:171-179 J.B. Forien, C. Fleck, P. Cloetens, G. Duda, P. Fratzl, E. Zolotoyabko, P. Zaslansky. "Compressive Residual Strains in Mineral Nanoparticles as a Possible Origin of Enhanced Crack Resistance in Human Tooth Dentin" Nano Lett. (2015), 15(6):3729-34 A. Cipitria, W. Wagermaier, P. Zaslansky, H. Schell, J.C. Reichert, P. Fratzl, D.W. Hutmacher, G.N. Duda, "BMP delivery complements the guiding effect of scaffold architecture without altering bone microstructure in critical-sized long bone defects: Amultiscale analysis" Acta Biomater. (2015), 23:282-94 E.L. Bortel, G.N. Duda, S. Mundlos, B.M. Willie, P. Fratzl, P. Zaslansky, "Long bone maturation is driven by pore closing: A quantitative tomography investigation of structural formation in young C57BL/6 mice" Acta Biomater. (2015), 22:92-102 I. Zanette, B. Enders, M. Dierolf, P. Thibault, R. Gradl, A. Diaz, M. Guizar-Sicairos, A. Menzel, F. Pfeiffer, P. Zaslansky, "Ptychographic X-ray nanotomography quantifies mineral distributions in human dentine" Sci Rep. (2015), 5:9210. doi: 10.1038/srep09210. M. Erko, O. Younes-Metzler, A. Rack, P. Zaslansky, SL. Young, G. Milliron, M. Chyasnavichyus, FG. Barth, P. Fratzl, V. Tsukruk, I. Zlotnikov, Y. Politi , "Micro- and nano-structural details of a spider's filter for substrate vibrations: relevance for lowfrequency signal transmission" J R Soc Interface. (2015), 12(104):20141111 B. Bayerlein, P. Zaslansky, Y. Dauphin, A. Rack, P. Fratzl, I. Zlotnikov1, " Self-Similar Mesostructure Evolution of the Growing Mollusk Shell Reminiscent of Thermodynamically Driven Grain Growth" Nat. Mater, (2014), 13(12):1102-7 M. Kerschnitzki, T. Zander, P. Zaslansky, P. Fratzl, R. Shahar, W. Wagermaier, "Rapid alterations of avian medullary bone material during the daily egg-laying cycle" Bone(2014) 69:109-17 F. Schulze, A. Dienelt, S. Geissler, P. Zaslansky, J. Schoon, K. Henzler, P. Guttmann, A. Gramoun, L.A. Crowe, L. Maurizi, J.-P. Vallée, H. Hofmann, G.N. Duda, A. Ode, "Amino-polyvinyl Alcohol Coated Superparamagnetic Iron Oxide Nanoparticles are Suitable for Monitoring of Human Mesenchymal Stromal Cells In Vivo" Small (2014) 10(21):4340-51 U. Tritschler, I. Zlotnikov, P. Zaslansky, P. Fratzl, H. Schlaad, H. Cölfen, "Hierarchicallystructured vanadium pentoxide-polymer hybrid materials" ACS Nano (2014) 8(5):5089- 104. P. Zaslansky, A. Maerten, P. Fratzl, "Apatite alignment and orientation at the Ångstrom and nanometer length scales shed light on the adaptation of dentine to whole tooth mechanical function" Bioinspired, Biomimetic and Nanobiomaterials (2013) 2(4):194-202,. U. Tritschler, I. Zlotnikov, P. Zaslansky, B. Aichmayer, P. Fratzl, H. Schlaad, H. Cölfen, "Hierarchical Structuring of Liquid Crystal Polymer-Laponite Hybrid Materials" Langmuir (2013) 29(35):11093-101 L. Kabalah-Amitai, B. Mayzel, P. Zaslansky, Y. Kauffmann, P. Clotens, B. Pokroy, "Unique crystallographic pattern in the macro to atomic structure of Herdmania momus vateritic spicules" J Struct Biol (2013) 183(2):191-198 A. Shipov, P. Zaslansky H. Riesemeier, G. Segev, A. Atkins, R. Shahar, "Unremodeledendochondral bone is a major architectural component of the cortical bone of the rat (Rattus norvegicus).", J Struct Biol (2013) 183(2):132-140, 2013 A. Maerten, P. Zaslansky, C. Mochales, T. Traykova, WD. Mueller, P. Fratzl, C. Fleck, "Characterizing the transformation near indents and cracks in clinically used dental yttriastabilized zirconium oxide constructs" Dent Mater (2013) 29(2):241-51 J. Seto, B. Busse, H.S. Gupta, C. Schäfer, S. Krauss, JWC. Dunlop, A. Masic, M. Kerschnitzki, P. Zaslansky, P. Boesecke, P. Catalá-Lehnen, T. Schinke, P. Fratzl, W. Jahnen-Dechent, "Accelerated Growth Plate Mineralization and Foreshortened Proximal Limb Bones in Fetuin-A Knockout Mice" PLoS ONE (2012) 7(10):e47338doi:10.1371/journal.pone.0047338 C. Fleck, P. Schüler, D. Meinel, P. Zaslansky, J. D. Currey, "Microstructural Features influencing failure in Macadamia nuts", Bioinspired, Biomimetic and Nanobiomaterials (2012) 1(2):67–75 G.R. Naveh, N. Lev-Tov Chattah, P. Zaslansky, R. Shahar, S. Weiner, "Tooth-PDL-bone complex: Response to compressive loads encountered during mastication - A review", Arch Oral Biol (2012) 57(12):1575-1584 A.S. Schenk, I. Zlotnikov, B. Pokroy, N. Gierlinger, A. Masic, P. Zaslansky, A.N. Fitch, O. Paris, T.H. Metzger, H. Cölfen, P. Fratzl, B.Aichmayer, "Hierarchical Calcite Crystals with Occlusions of a Simple Polyelectrolyte Mimic Complex Biomineral Structures", Adv Funct Mater (2012) 22(22):4668-4676 S. Bentov, P. Zaslansky, A. Al-Sawalmih, A. Masic, P. Fratzl, A. Sagi A. Berman, B. Aichmayer, "Enamel-like apatite crown covering amorphous mineral in a crayfish mandible" , Nat. Commun (2012) 3:839, doi: 10.1038/ncomms1839 Y. Politi, M. Priewasser, E. Pippel, P. Zaslansky, J. Hartmann, S. Siegel, C. Li, FG. Barth P. Fratzl, "A Spider's Fang: How to Design an Injection Needle Using Chitin-Based Composite Material", Adv Funct Mater (2012) 22(12):2519–2528 P. Zaslansky, P. Fratzl, A. Rack, M-K Wu, P. R. Wesselink and H. Shemesh, "Identification of root filling interfaces by microscopy and tomography methods", Int. Endod. (2011) J 44(5):395-401 C. Mochales, A. Märten, A. Rack, P. Cloetens, W.D. Müller, P. Zaslansky, C. Fleck, "Monoclinic phase transformations of zirconia-based dental prostheses, induced by clinically practiced surface manipulations", Acta Biomater (2011) 7(7):2994-3002 A. Maerten, P. Fratzl, O. Paris, P. Zaslansky, "On the mineral in collagen of human crown dentine". Biomaterials (2010) 31 (20):5479-90 Y. Politi, D.R. Batchelor, P. Zaslansky, B.F. Chmelka, J.C. Weaver, I. Sagi, S. Weiner, L. Addadi, "Role of Magnesium Ion in the Stabilization of Biogenic Amorphous Calcium Carbonate: A Structure-Function Investigation", Chem Mater (2010) 22 (1):161-166 P. Zaslansky, S. Zabler, P. Fratzl, "3D variations in human crown dentin tubule orientation: a phase-contrast microtomography study", Dent Mater (2010) 26 (1):e1-10 U. Blunck, P. Zaslansky, "Enamel Margin Integrity of Class I One-bottle All-in-one Adhesives-based Restorations", J Adhes Dent (2010) 13(1):23-9 H. Gupta, S. Krauss, J. Seto, W. Wagermaier, M. Kerschnitzki, G. Benecke, P. Zaslansky, P. Boesecke, S.S. Funari, H.O.K Kirchner, P. Fratzl, "Nanoscale deformation mechanisms in bone", Bone (2009) 44 (1):S33-4 J. Seto, H.S. Gupta, P. Zaslansky, H. D. Wagner, P. Fratzl, "Tough Lessons From Bone: Extreme Mechanical Anisotropy at the Mesoscale", Adv Func Mater (2008) 18(13):1905- 1911 R. Shahar, P. Zaslansky, M. Barak, A.A. Friesem, J.D. Currey, S. Weiner, "Anisotropic Poisson's ratio and compression modulus of cortical bone determined by speckle interferometry", J Biomech (2007) 40:252-264 U. Blunck, P. Zaslansky, "Effectiveness of All-in-one Adhesive Systems Tested by Thermocycling Following Short and Long-term Water storage", J Adhes Dent (2007) 9(2):231-240 S. Zabler, A. Rueda, A. Rack, H. Riesemeier, P. Zaslansky, I. Manke, F. Garcia-Moreno, J. Banhart, "Coarsening of grain-refined semi-solid Al–Ge32 alloy: X-ray microtomography and in situ radiography", Acta Mater (2007) 55(15):5045-5055 S. Zabler, P. Cloetens, P. Zaslansky, "Fresnel-propagated sub-micron X-ray imaging of water-immersed tooth dentin", Opt Lett (2007) 32(20):2987-2989 H.S. Gupta , J. Seto, W. Wagermaier, P. Zaslansky, P. Boesecke, P. Fratzl, "Cooperative deformation of mineral and collagen in bone at the nanoscale", PNAS (2006) 103:17741- 17746 P. Zaslansky, A.A. Friesem, S. Weiner, "Structure and mechanical properties of the soft zone separating bulk dentin and enamel in crowns of human teeth: Insight into tooth function", J Struct Biol (2006) 153(2):188-199 S. Weiner, F. Nudelman, E. Sone, P. Zaslansky, L. Addadi, "Mineralized biological materials: A perspective on interfaces and interphases designed over millions of years",Biointerphases 1 (2006) (2):12–14 P. Zaslansky, R. Shahar, A. A. Friesem, S. Weiner, "Relations Between Shape, MaterialsProperties and Function in Biological Materials Using Laser Speckle Interferometry: Insitu Tooth Deformation", Adv Funct Mater (2006) 16:1925-1936 S. Zabler, H. Riesemeier, P. Fratzl and P. Zaslansky, "Fresnel-propagated imaging for the study of human tooth dentin by partially coherent x-ray tomography", Opt Express (2006) 14 (19):8584-8597 P. Zaslansky, J.D. Currey, A.A. Friesem, S. Weiner, "Phase shifting speckle interferometry for determination of strain and Young's modulus of mineralized biological materials: a study of tooth dentin compression in water", J Biomed Opt (2005) 10 (2): 024020 Book chapters: R. Shahar, P. Zaslansky, "Whole organ deformation analysis by digital optical metrology methods" In DiMasi E & Gower L (eds) Biomineralization Handbook Taylor & Francis, (2014) P. Zaslansky, "Dentin"; In Fratzl P (ed) Collagen: Structure and Mechanics, Springer New York, (2008) P. Zaslansky, S. Weiner, "Design Strategies of Human Teeth: Biomechanical Adaptations" In Bauerlein, E, Behrens, P & Epple, M (eds) Handbook of Biomineralization. Vol. 3. Wiley-VCH, Weinheim, (2007)

Lebenslauf Dr. med. dent., PhD, Paul Zaslansky

2000-2005 PhD, Weizmann Institute of Science, Rehovot, Israel. Joint project bridging the Optics group, Department of Complex Systems, Faculty of Physics and the Biomineralization group, Department of Structural Biology, Faculty of Chemistry. PhD Thesis: Human tooth-structure function relations: an electron microscopy and laser speckle interferometry optical metrology study, conducted under the supervision of Prof. S. Weiner (Chemistry) and Prof. A.A. Friesem (Physics)
1985-1991 Doctor of Medical Dentistry (DMD), combined with a Bachelor of Medical Sciences (B.Med.Sc.), The Hebrew University-Hadassah School of Dental Medicine. DMD Thesis: "Computerized characteristics of CT-sialography of space occupying lesions in the parotid gland", supervisors: Prof. G. Zajicek and Dr. D. Schwartz-Arad
Professional Career:  
seit 07/2016 Staff scientist- Dept. of Operative and Preventive Dentristry, CharitéUniversitätsmedizin Berlin, Germany.
2011-2016 Staff scientist, Julius Wolff Institute (JWI) & Center for Musculoskeletal Surgery (CMSC), CharitéUniversitätsmedizin Berlin, Germany. Emphasis on: High resolution characterization of microstructure, properties and architecture of dentin in human teeth and bone in rodents (mice) and fish. Expertise in non-destructive, non-contact measurement methods - experiment, analysis and validation: tomography (both absorption & interference-based phase contrast-enhanced), speckle correlation (by interferometry and by computational correlation), X-ray diffraction and electron microscopy. Experiments coupled with mechanical testing of teeth and bone.
2005-2011 Postdoctoral researcher (2005/06)/Staff scientist(from 2007), Department of Biomaterials, Max-Planck-Institute of Colloids and Interfaces, Potsdam, Germany. Emphasis on: Multi length scale characterization of hard tissue (teeth and bones), studies of architecture and arrangement of the Composite components. In situ (SEM, Synchrotron) mechanical testing and nondestructive characterization by combined absorption and phase-contrast enhanced tomography, electron and optical microscopy, spectroscopy and laser-speckle interferometry.
2000- 2005 PhD research - Weizmann Institute of Science, Rehovot, Israel Mechanical and optical studies of structure and function in human teeth; Precision measurements of structural microdeformations using non-contact coherent optical metrology by laser holography and speckle interferometry.
1992-2005 Dental Surgeon: Patient treatment in private practice. Practice limited to advanced restorative techniques: Adhesive composite and ceramic restorations; Minimal invasive dentistry (MID), general practitioner